There have been numerous revolutions in agriculture, which have improved competency and led to record-breaking yields and gains. Around 10,000 BC, the first agricultural revolution made it possible for people to settle down, giving rise to the first societies and civilizations in human history. Other revolutions introduced mechanization (1900–1930), which sparked the creation of agrochemicals and resistant plant types (the "Green Revolution" in the 1960s), as well as the development of genetic modification technologies (from 1990 to 2005). The most recent of these is the “smart farming revolution”, which will contribute to humanity's survival and future prosperity. Smart farming presents numerous prospects for the pervasive interconnection and database computer technology as part of Industry 4.0. Smart agriculture is also known as agriculture 4.0, digital farming, or smart farming is the idea of agricultural practice in a creative manner while utilizing cutting-edge technology to improve the quantity and quality of agricultural goods. New methods to assure global food safety are part of the future of the food manufacturing industry. It enables farmers to boost yields while using less resources. Fertilizers, labor, seeds, and water are just a few of the resources that can be saved. Smart farming has a variety of applications, including land management, selection of varieties, minimizing the use of synthetic fertilizers and pesticides inputs, and then replacing them with environmentally friendly inputs, nano emulsions, and the use of the modern technology, including mechanization, big data, robots, internet of things, and artificial intelligence. One of the latest smart farming and precision agriculture use of drones. Drones can simplify monitoring tasks for large-scale agricultural areas, collecting information and data on soil and plant conditions, water requirements, and plant health. Drones can also be used to control and prevent the expansion of pests and diseases. Although there has been a lot of study and development in those related issues, these technologies aren't widely used and it has not been successfully implemented or integrated in any of developing countries. As a respond to those issues, Faculty of Agriculture, Universitas Andalas will conducting 2nd Agrifood System International Conference with the theme: Research advancement and innovations in agroecology and smart agrifood system. The objectives of this event are to strengthening and developing collaborations and partnerships by inviting all participants and invited speakers for scientific progress in agriculture specifically on related with the given theme. Parallel panels with presenters chosen from the call for papers will then examine various aspects of agroecology and smart agrifood as the program continues. Each panel will also include a number of speakers who is expertise in that field. Opportunities for post- conference publication in a variety of media, including international journals, national journals, and conference proceedings, will be made available.